产品名称
Peroxiredoxin 3 (17J3) Rabbit Monoclonal Antibody
别名
AOP1; HBC189; MER5; peroxiredoxin 3; Peroxiredoxin III; PRDX3; PRO1748; Protein MER5 homolog; PRX III; PRX3; SP22;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P30048
免疫原
A synthetic peptide of human Peroxiredoxin 3/PRDX3
稀释度
WB: 1:2000-1:10000 IHC: 1:50 ICC/IF: 1:50 FC: 1:20 IP: 1:20-1:100
注意事项
Peroxiredoxin 3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Mitochondrion {ECO:0000250|UniProtKB:P35705}. Cytoplasm. Early endosome. Note=Localizes to early endosomes in a RPS6KC1-dependent manner.
功能
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides (PubMed:
7733872, PubMed:
17707404). Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol (PubMed:
12492477).
