产品名称
Calpain 2 (3O9) Rabbit Monoclonal Antibody
别名
CALP80; Calpain M type; Calpain-2 large subunit; Calpain2; CANP2; CANPL2; CANPml; Capa2; CAPN2; M calpain; mCANP; Millimolar calpain;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P17655
注意事项
Calpain 2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon Ca(2+) binding
功能
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:
17650508). Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity).
