产品名称
KIF3A (8J10) Rabbit Monoclonal Antibody
别名
KIF 3; KIF 3A; Kifl; Kinesin family member 3A; Kinesin like protein KIF 3A; Kinesin-like protein KIF3A; Kns3;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q9Y496
稀释度
WB 1:500~1:2000 IP 1:50
注意事项
KIF3A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cytoplasm, cytoskeleton. Cell projection, cilium {ECO:0000250|UniProtKB:P28741}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to the subdistal appendage region of the centriole.
功能
Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitment of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole.