产品名称
OGG1 (15C8) Rabbit Monoclonal Antibody
别名
8 hydroxyguanine DNA glycosylase; AP lyase; HMMH; HOGG1; MMH; MUTM; N glycosylase; Ogg1; OGH 1;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
O15527
注意事项
OGG1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Nucleus, nucleoplasm. Nucleus speckle. Nucleus matrix. Note=Together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells [Isoform 2A]: Mitochondrion.
功能
DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N- methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.
