RM5349

APOC3 (12Q8) Rabbit Monoclonal Antibody

APOC3; APO C3; Apo CIII; ApoC III; APOC3; ApoCIII; Apolipoprotein C III; Apolipoprotein C3;

Affinity-chromatography

常规抗体

APOC3

WB

Human

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

345

P02656

WB 1:500~1:2000 IHC 1:50~1:200

11kDa

Rabbit IgG

APOC3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Liver..

Secreted

Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma (PubMed:18201179, PubMed:22510806). Plays a multifaceted role in triglyceride homeostasis (PubMed:18201179, PubMed:22510806). Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride- rich lipoproteins (TRLs) (PubMed:18201179, PubMed:22510806). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors (PubMed:18201179, PubMed:22510806). Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners (PubMed:18408013).

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