RM5348

CHD3 (3C1) Rabbit Monoclonal Antibody

CHD-3; Chd3; Chd7; hZFH; Mi2 ALPHA; Prp7; ZFH; Zinc finger helicase;

Affinity-chromatography

常规抗体

CHD3

WB

Human,Mouse,Rat

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

1107

Q12873

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50

227kDa

Rabbit IgG

CHD3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Widely expressed..

Nucleus, PML body. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Associates with centrosomes in interphase and mitosis.

Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones (PubMed:9804427, PubMed:30397230). Involved in transcriptional repressiobn as part of the NuRD complex (PubMed:27068747). Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity (PubMed:17626165).

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