RM5339

p23 (14Z14) Rabbit Monoclonal Antibody

cPGES; Cytosolic prostaglandin E synthase; Hsp90 co chaperone; P23; Sid 3177; TEBP;

Affinity-chromatography

常规抗体

PTGES3

P23, TEBP

WB

Human,Mouse,Rat

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

10728

Q15185

A synthetic peptide of human p23/PTGES3

WB: 1:2000-1:100001:20 IP: 1:20

23kDa

19kDa

Rabbit IgG

p23 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Cytoplasm {ECO:0000250|UniProtKB:Q3ZBF7}.

Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (PubMed:24711448).

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