产品名称
PON1 (1Q14) Rabbit Monoclonal Antibody
别名
A esterase 1; Aromatic esterase 1; Arylesterase 1; Arylesterase B type; ESA; Esterase A; K-45; MVCD5; Paraoxonase 1; Paraoxonase B type; PON; PON1; Serum aryldiakylphosphatase;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P27169
免疫原
A synthetic peptide of human PON1
稀释度
WB: 1:2000-1:10000 IP: 1:20
注意事项
PON1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Plasma, associated with HDL (at protein level). Expressed in liver, but not in heart, brain, placenta, lung, skeletal muscle, kidney or pancreas.
细胞定位
Secreted, extracellular space.
功能
Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
