BD-PN0889

MAL Rabbit Polyclonal Antibody

常规抗体

MAL

Myelin and lymphocyte protein (T-lymphocyte maturation-associated protein)

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

4118

P21145

https://www.uniprot.org/uniprotkb/P21145/entry

O09198

http://www.uniprot.org/uniprot/O09198

Q64349

http://www.uniprot.org/uniprot/O54941Q64349

Synthesized peptide derived from human protein . at AA range: 70-150

MAL Polyclonal Antibody detects endogenous levels of protein.

WB 1:500-2000 ELISA 1:5000-20000

16kD

-20°C/1 year

Polyclonal, Rabbit,IgG

The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. [provided by RefSeq, May 2012],

Brain,Lung,Lymphocyte,Placenta,

Membrane; Multi-pass membrane protein.

developmental stage:Expressed in the intermediate and late stages of T-cell differentiation.,function:Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane. Could be involved in myelin biogenesis and/or myelin function.,PTM:Lipoprotein.,similarity:Belongs to the MAL family.,similarity:Contains 1 MARVEL domain.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.