RM5320

Fibulin 5 (11T19) Rabbit Monoclonal Antibody

Fibulin-5; FIBL-5; Fibulin 5; FIBL 5; Fibulin5; FIBL5; Dance; Urine p50 protein; UP50; DANCE;

Affinity-chromatography

常规抗体

FBLN5

DANCE

WB

Human,Mouse

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

10516

Q9UBX5

WB 1:500~1:2000

50kDa

Rabbit IgG

Fibulin 5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Expressed in skin fibroblasts (at protein level)(PubMed:17035250). Expressed predominantly in heart, ovary, and colon but also in kidney, pancreas, testis, lung and placenta. Not detectable in brain, liver, thymus, prostate, or peripheral blood leukocytes (PubMed:10428823).

Secreted. Secreted, extracellular space, extracellular matrix. Note=co-localizes with ELN in elastic fibers.

Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (PubMed:18185537). Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity). Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling (PubMed:10428823). May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed:17255108).

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