产品名称
LOX (2U4) Rabbit Monoclonal Antibody
别名
lox; LYOX; Lysyl oxidase; Protein lysine 6 oxidase;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P28300
稀释度
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:60
注意事项
LOX Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Heart, placenta, skeletal muscle, kidney, lung and pancreas.
细胞定位
Secreted. Secreted, extracellular space
功能
Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin (PubMed:
26838787). Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture (By similarity).
