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Annexin A2 (5A11) Rabbit Monoclonal Antibody

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产品基本信息

产品货号
RM5261
产品名称
Annexin A2 (5A11) Rabbit Monoclonal Antibody
别名
Annexin A2; Annexin II; Annexin-2; Calpactin I heavy chain; PAP-IV; Protein I; p36; ANXA2; ANX2; ANX2L4; CAL1H; LPC2D; Annexin2; HEL S 270;
纯度
Affinity-chromatography
类别
常规抗体
基因名称
ANXA2
蛋白名称
ANX2, ANX2L4, CAL1H, LPC2D
推荐应用
WB
反应种属
Human,Mouse,Rat
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Gene ID
302
Human Swissprot No.
P07355
免疫原
A synthetic peptide of human Annexin A2
稀释度
WB: 1:1000 IHC: 1:20 ICC/IF: 1:50 FC: 1:20
参考分子量
38kDa
预测分子量
39kDa
同种型
Rabbit IgG
注意事项
Annexin A2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Secreted, extracellular space, extracellular matrix, basement membrane. Melanosome. Note=In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism
功能
Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed:18799458, PubMed:24808179, PubMed:22848640).
期货
现货

Western blot analysis of Annexin A2 expression in HeLa cell lysate.

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