产品名称
Profilin1 (15O6) Rabbit Monoclonal Antibody
别名
Actin binding protein; ALS18; Epididymis tissue protein Li 184a; PFN 1; Pfn; PFN1; Profilin1; ProfilinI;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P07737
免疫原
A synthetic peptide of human Profilin 1
稀释度
WB: 1:2000 IHC: 1:50 ICC/IF: 1:50 FC: 1:100 IP: 1:20
注意事项
Profilin1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in epididymis (at protein level).
细胞定位
Cytoplasm, cytoskeleton.
功能
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.
