产品名称
GATA1 (2P13) Rabbit Monoclonal Antibody
别名
Erythroid transcription factor; Eryf1; GATA-binding factor 1; GATA-1; GF-1; NF-E1 DNA-binding protein; GATA1; ERYF1; GF1;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P15976
免疫原
Recombinant protein of human GATA1
稀释度
WB: 1:2000 IHC: 1:20 ICC/IF: 1:50 IP: 1:20 ChIP: 1:20
注意事项
GATA1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
功能
Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells. Activates the transcription of genes involved in erythroid differentiation of K562 erythroleukemia cells, including HBB, HBG1/2, ALAS2 and HMBS (PubMed:
24245781).