产品名称
SOS1 (5D2) Rabbit Monoclonal Antibody
别名
alternate SOS1; GF1; GGF1; GINGF; gingival fibromatosis; HGF; NS4; Sos1;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q07889
免疫原
Recombinant protein of human SOS1
稀释度
WB: 1:1000 IHC: 1:100 ICC/IF: 1:200
注意事项
SOS1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in gingival tissues.
功能
Promotes the exchange of Ras-bound GDP by GTP (PubMed:
8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF (PubMed:
17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity).
