RM5226

MUC5AC (10H12) Rabbit Monoclonal Antibody

Apomucin; Gastric mucin; LeB; MUC5AC; Mucin 5AC oligomeric mucus/gel forming; TBM;

Affinity-chromatography

常规抗体

MUC5AC {ECO:0000303|PubMed:11535137, ECO:0000312|HGNC:HGNC:7515}

WB

Human

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

4586

P98088

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

586kDa

Rabbit IgG

MUC5AC Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum.

Secreted.

Gel-forming glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system (PubMed:14535999, PubMed:14718370). Interacts with H.pylori in the gastric epithelium, Barrett's esophagus as well as in gastric metaplasia of the duodenum (GMD) (PubMed:14535999).

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