产品名称
XRCC1 (19W2) Rabbit Monoclonal Antibody
别名
DNA repair protein XRCC1; RCC; X ray repair complementing defective repair in chinese hamster; XRCC 1;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P18887
免疫原
A synthetic peptide of human XRCC1
稀释度
WB: 1:1000 IHC: 1:50 ICC/IF: 1:50
注意事项
XRCC1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in fibroblasts, retinal pigmented epithelial cells and lymphoblastoid cells (at protein level)
细胞定位
Nucleus. Note=Moves from the nucleoli to the global nuclear chromatin upon DNA damage
功能
Involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes. Probably during DNA repair, negatively regulates ADP-ribose levels by modulating ADP- ribosyltransferase PARP1 activity.
