产品名称
EGF (12M6) Rabbit Monoclonal Antibody
别名
Beta urogastrone; Egf; Epidermal growth factor; HOMG4; Pro epidermal growth factor; URG; Urogastrone;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P01133
稀释度
WB 1:500~1:2000 IP 1:50
注意事项
EGF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in kidney, salivary gland, cerebrum and prostate.
细胞定位
Membrane; Single-pass type I membrane protein.
功能
EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro (PubMed:
10964941).
