BD-PN0875

MNX1 Rabbit Polyclonal Antibody

常规抗体

MNX1 HLXB9

Motor neuron and pancreas homeobox protein 1 (Homeobox protein HB9)

WB

Human,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.

3110

P50219

https://www.uniprot.org/uniprotkb/P50219/entry

Q9QZW9

http://www.uniprot.org/uniprot/Q9QZW9

Synthesized peptide derived from human protein . at AA range: 260-340

MNX1 Polyclonal Antibody detects endogenous levels of protein.

WB 1:500-2000 ELISA 1:5000-20000

44kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],

Expressed in lymphoid and pancreatic tissues.

Nucleus.

Maturity onset diabetes of the young;

disease:Defects in MNX1 are a cause of Currarino syndrome [MIM:176450]. The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. The syndrome occurs in the majority of patients as an autosomal dominant trait.,function:Putative transcription factor involved in pancreas development and function.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Expressed in lymphoid and pancreatic tissues.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.