RM5204

TNF Receptor II (19A16) Rabbit Monoclonal Antibody

CD120b; p75 TNF receptor; p80 TNF alpha receptor; Soluble TNFR1B variant 1; TBP-2; TBPII; TNF R75; TNFBR; TNFR-II; TNFR1B; TNFR2; TNFR80; TNFRII; Tnfrsf1b;

Affinity-chromatography

常规抗体

TNFRSF1B

TNFBR, TNFR2

WB

Human,Mouse,Rat

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

7133

P20333

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50

48kDa

Rabbit IgG

TNF Receptor II Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

[Isoform 1]: Cell membrane; Single-pass type I membrane protein [Tumor necrosis factor-binding protein 2]: Secreted

Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.

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