RM5199

GRP94 (2K1) Rabbit Monoclonal Antibody

Endoplasmin; GRP-94; gp96 homolog; HSP90B1; GRP 94; TRA1;

Affinity-chromatography

常规抗体

HSP90B1

GRP94, TRA1

WB

Human,Mouse

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

7184

P14625

WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

92kDa

Rabbit IgG

GRP94 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Endoplasmic reticulum lumen. Sarcoplasmic reticulum lumen {ECO:0000250|UniProtKB:P41148}. Melanosome Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity). When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD) (PubMed:18264092). Has ATPase activity (By similarity). May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum- Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10 (PubMed:32272059).

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