产品名称
TIA1 (2C12) Rabbit Monoclonal Antibody
别名
Nucleolysin TIA 1 isoform p40; p40 TIA 1; TIA1 protein; TIAL1; TIAR;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P31483
稀释度
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
注意事项
TIA1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cytoplasm, Stress granule. Nucleus. Note=Accumulates in cytoplasmic stress granules (SG) following cellular damage.
功能
Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.