产品名称
Bid (6Y3) Rabbit Monoclonal Antibody
别名
BID isoform ES(1b); BID isoform L(2); BID isoform Si6; FP497; p11 BID; p13 BID; p15 BID; p22 BID;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P55957
免疫原
A synthetic peptide of human Bid
稀释度
WB: 1:1000 IHC: 1:20 ICC/IF: 1:20 FC: 1:20 IP: 1:20
注意事项
Bid Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
[Isoform 2]: Expressed in spleen, pancreas and placenta (at protein level). [Isoform 4]: Expressed in lung and pancreas (at protein level).
细胞定位
Cytoplasm. Mitochondrion membrane. Mitochondrion outer membrane. Note=When uncleaved, it is predominantly cytoplasmic. [BH3-interacting domain death agonist p13]: Mitochondrion membrane {ECO:0000250|UniProtKB:P70444}. Note=Associated with the mitochondrial membrane. {ECO:0000250|UniProtKB:P70444} [Isoform 3]: Cytoplasm
功能
Induces caspases and apoptosis (PubMed:
14583606). Counters the protective effect of BCL2 (By similarity).