产品名称
CD62P (16H10) Rabbit Monoclonal Antibody
别名
P-selectin; CD62 antigen-like family member P; Granule membrane protein 140; GMP-140; PADGEM; CD62P; SELP; GMRP;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P16109
稀释度
WB 1:500~1:2000 IHC 1:50~1:200
注意事项
CD62P Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface
细胞定位
Cell membrane; Single-pass type I membrane protein
功能
Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG.
