产品名称
MOT2 Rabbit Polyclonal Antibody
蛋白名称
Monocarboxylate transporter 2 (MCT 2) (Solute carrier family 16 member 7)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O60669
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O60669/entry
Mouse Swissprot No.
O70451
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O70451
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q63344
免疫原
Synthesized peptide derived from human protein . at AA range: 220-300
特异性
MOT2 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012],
组织表达
Detected in heart and in blood lymphocytes and monocytes (at protein level). High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and Leukocyte. Restricted expression in normal tissues, but widely expressed in cancer cells.
细胞定位
Cell membrane ; Multi-pass membrane protein .
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
