产品名称
IL4 (9S15) Rabbit Monoclonal Antibody
别名
BCGF1; Binetrakin; BSF1; IGG1 induction factor; IL4; Il4e12;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P05112
免疫原
A synthetic peptide of human IL4
稀释度
WB: 1:1000 ICC/IF: 1:50 FC: 1:20
注意事项
IL4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
功能
Participates in at least several B-cell activation processes as well as of other cell types (PubMed:
3016727). It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages (By similarity). Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4 (By similarity).
