产品名称
CD59 (6G2) Rabbit Monoclonal Antibody
别名
CD59 glycoprotein; HRF20; MAC-IP; MEM43 antigen; MACIF; MIRL; Protectin; MIC11; MIN1; p18 20;
纯度
Affinity-chromatography
蛋白名称
MIC11, MIN1, MIN2, MIN3, MSK21
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P13987
稀释度
WB 1:1000~1:5000 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
注意事项
CD59 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Soluble form found in a number of tissues
功能
Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
