产品名称
IMP1L Rabbit Polyclonal Antibody
蛋白名称
Mitochondrial inner membrane protease subunit 1 (EC 3.4.21.-) (IMP1-like protein)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q96LU5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96LU5/entry
Mouse Swissprot No.
Q9CQU8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9CQU8
免疫原
Synthesized peptide derived from human protein . at AA range: 70-150
特异性
IMP1L Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The mitochondrial inner membrane peptidase (IMP) complex generates mature, active proteins in the mitochondrial intermembrane space by proteolytically removing the mitochondrial targeting presequence of nuclear-encoded proteins. IMP1 and IMP2 (IMMP2L; MIM 605977) are the catalytic subunits of the IMP complex (Burri et al., 2005 [PubMed 15814844]).[supplied by OMIM, Sep 2008],
细胞定位
Mitochondrion inner membrane .
功能
function:Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.,similarity:Belongs to the peptidase S26 family. IMP1 subfamily.,subunit:Heterodimer of 2 subunits, IMMPL1 and IMMPL2.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.