产品名称
CD80 (4F8) Rabbit Monoclonal Antibody
别名
B7.1; BB1; CD28 antigen ligand 1; CD28LG1; CD80; CD80 antigen; T-lymphocyte activation antigen CD80;
纯度
Affinity-chromatography
蛋白名称
CD28LG, CD28LG1, LAB7
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P33681
免疫原
A synthetic peptide of human CD80
稀释度
WB: 1:1000 IHC: 1:20-1:500
注意事项
CD80 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed on activated B-cells, macrophages and dendritic cells
细胞定位
Membrane; Single-pass type I membrane protein.
功能
Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.