产品名称
SERPINA1 (2F7) Rabbit Monoclonal Antibody
别名
Serpin A1; Short peptide from AAT; SPAAT; AAT;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P01009
注意事项
SERPINA1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Ubiquitous. Expressed in leukocytes and plasma.
细胞定位
Secreted. Endoplasmic reticulum. Note=The S and Z allele are not secreted effectively and accumulate intracellularly in the endoplasmic reticulum
功能
Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.
