产品名称
Neutrophil Elastase (9J14) Rabbit Monoclonal Antibody
别名
ELA2; ELANE; Elastase 2; Medullasin; Neutrophil elastase; PMN E; SCN1;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P08246
稀释度
WB 1:500~1:2000 IHC 1:100~1:500 ICC/IF 1:50~1:200 FC 1:30
注意事项
Neutrophil Elastase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Bone marrow cells. Neutrophil (PubMed:10947984).
细胞定位
Cytoplasmic vesicle, phagosome. Note=Localized in phagolysosomes following ingestion of E.coli by neutrophils
功能
Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis (PubMed:
15140022). Capable of killing E.coli but not S.aureus in vitro; digests outer membrane protein A (ompA) in E.coli and K.pneumoniae (PubMed:
10947984).
