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LYVE1 (19I3) Rabbit Monoclonal Antibody

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产品基本信息

产品货号
RM5038
产品名称
LYVE1 (19I3) Rabbit Monoclonal Antibody
别名
CRSBP 1; CRSBP-1; CRSBP1; hyaluronic acid receptor;
纯度
Affinity-chromatography
类别
常规抗体
基因名称
LYVE1
蛋白名称
CRSBP1, HAR, XLKD1
推荐应用
WB
反应种属
Human,Mouse,Rat
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Gene ID
10894
Human Swissprot No.
Q9Y5Y7
稀释度
WB 1:500~1:2000
预测分子量
35kDa
同种型
Rabbit IgG
注意事项
LYVE1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Mainly expressed in endothelial cells lining lymphatic vessels.
细胞定位
Membrane; Single- pass type I membrane protein Note=Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface
功能
Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
期货
现货

Western blot analysis of LYVE1 expression in A549 cell lysate.

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