RM5033

PDIA6 (17M12) Rabbit Monoclonal Antibody

PDIA6; ERP5, P5, TXNDC7; ER protein 5; ERp5;

Affinity-chromatography

常规抗体

PDIA6

ERP5, P5, TXNDC7

WB

Human,Mouse,Rat

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

10130

Q15084

WB 1:500~1:2000 ICC/IF 1:50~1:200 FC 1:50

48kDa

Rabbit IgG

PDIA6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Expressed in platelets (at protein level).

Endoplasmic reticulum lumen. Cell membrane. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545)

May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:12204115). Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (PubMed:24508390). May also regulate the UPR via the EIF2AK3 UPR sensor (PubMed:24508390). Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (PubMed:15466936).

现货