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Catenin gamma (14M19) Rabbit Monoclonal Antibody

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产品基本信息

产品货号
RM5032
产品名称
Catenin gamma (14M19) Rabbit Monoclonal Antibody
别名
ARVD12; Catenin gamma; CTNNG; Desmoplakin III; Desmoplakin-3; DP3; DPIII; gamma-catenin; Junction plakoglobin; JUP; PDGB; PKGB; PLAK;
纯度
Affinity-chromatography
类别
常规抗体
基因名称
JUP
蛋白名称
CTNNG, DP3
推荐应用
WB
反应种属
Human
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Gene ID
3728
Human Swissprot No.
P14923
免疫原
Recombinant protein of human gamma Catenin
稀释度
WB: 1:2000 IHC: 1:50 ICC/IF: 1:100 FC: 1:20
参考分子量
82kDa
预测分子量
82kDa
同种型
Rabbit IgG
注意事项
Catenin gamma Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cell junction, adherens junction. Cell junction, desmosome. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein Note=Cytoplasmic in a soluble and membrane-associated form
功能
Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE- cadherin function in endothelial cells. Can replace beta-catenin in E- cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).
期货
现货

Western blot analysis of Catenin gamma expression in (1) A431 cell lysate; (2) NIH 3T3 cell lysate; (3) C6 cell lysate.

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