产品名称
TGF beta 1 (3M4) Rabbit Monoclonal Antibody
别名
CED; diaphyseal dysplasia 1, progressive; DPD1; TGF-beta 1; TGFB1;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P01137
注意事项
TGF beta 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Highly expressed in bone (PubMed:11746498, PubMed:17827158). Abundantly expressed in articular cartilage and chondrocytes and is increased in osteoarthritis (OA) (PubMed:11746498, PubMed:17827158). Colocalizes with ASPN in chondrocytes within OA lesions of articular cartilage (PubMed:17827158)
细胞定位
[Latency-associated peptide]: Secreted, extracellular space, extracellular matrix
功能
Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.