产品名称
VWF (9L15) Rabbit Monoclonal Antibody
别名
VWF; von Willebrand factor; von Willebrand antigen II; F8VWF;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P04275
稀释度
WB 1:500~1:2000 IHC 1:50~1:200
注意事项
VWF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Secreted. Secreted, extracellular space, extracellular matrix. Note=Localized to storage granules
功能
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet- surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.