产品名称
mGluR1 (2N7) Rabbit Monoclonal Antibody
别名
GRM1A; mGlu1; GPRC1A; MGLUR1; SCAR13; MGLUR1A;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q13255
免疫原
A synthetic peptide of human mGluR1a
注意事项
mGluR1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cell membrane; Multi-pass membrane protein
功能
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol- calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum (PubMed:
24603153, PubMed:
28886343, PubMed:
7476890). May function in the light response in the retina (By similarity).
