产品名称
VWF (9L15) Rabbit Monoclonal Antibody
别名
VWF; von Willebrand factor; von Willebrand antigen II; F8VWF;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P04275
注意事项
VWF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Secreted. Secreted, extracellular space, extracellular matrix. Note=Localized to storage granules
功能
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet- surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
