产品名称
mGluR2 (11P14) Rabbit Monoclonal Antibody
别名
GRM2; Glutamate receptor homolog; GPRC1B; MGlu2; Metabotropic; GLUR2; MGLUR2;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q14416
免疫原
A synthetic peptide of human Metabotropic Glutamate Receptor 2
稀释度
WB: 1:2000-1:10000 IHC: 1:50 ICC/IF: 1:50 FC: 1:20
注意事项
mGluR2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Detected in brain cortex (at protein level). Widely expressed in different regions of the adult brain as well as in fetal brain.
细胞定位
Cell membrane; Multi-pass membrane protein. Cell junction, synapse. Cell projection, dendrite
功能
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
