产品名称
Caspase-10 (1R16) Rabbit Monoclonal Antibody
别名
Apoptotic protease Mch4; CASP10; Caspase10; FLICE2; ICE like apoptotic protease 4; FADD-like ICE2;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q92851
免疫原
Recombinant protein of human Caspase-10
稀释度
WB: 1:2000 IHC: 1:20 FC: 1:50 IP: 1:20
注意事项
Caspase-10 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Detectable in most tissues. Lowest expression is seen in brain, kidney, prostate, testis and colon
功能
Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.
