产品名称
Phospho-B Raf (T401) (6C16) Rabbit Monoclonal Antibody
别名
B-RAF; B-RAF proto-oncogene serine/threonine-protein kinase; BRAF1; RAFB1; RMIL; RMIL serine/threonine-protein kinase; c-RMIL; kinase B-Raf;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P15056
免疫原
A synthetic phosphopeptide corresponding to residues surrounding
Thr401 of human B Raf
稀释度
WB: 1:1000 ICC/IF: 1:50 IP: 1:20
注意事项
Phospho-B Raf (T401) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Nucleus. Cytoplasm. Cell membrane. Note=Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes.
功能
Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable). Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway (PubMed:
21441910, PubMed:
29433126). May play a role in the postsynaptic responses of hippocampal neurons (PubMed:
1508179).
