RM4929

Hsp75 (2S18) Rabbit Monoclonal Antibody

HSP75; HSP 75; HSP90L; TRAP-1;

Affinity-chromatography

常规抗体

TRAP1

HSP75

WB

Human

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

10131

Q12931

WB 1:500~1:2000 IP 1:50

80kDa

Rabbit IgG

Hsp75 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung, placenta and bladder. Expression is highly reduced in bladder cancer and renal cell carcinoma specimens compared to healthy tissues, but it is increased in other type of tumors

Mitochondrion. Mitochondrion inner membrane Mitochondrion matrix

Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

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