产品名称
Cdc23/APC8 (4Z9) Rabbit Monoclonal Antibody
别名
CDC23; ANAPC8; APC8; Cell division cycle 23; CUT23; Cyclosome subunit 8;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q9UJX2
稀释度
WB 1:500~1:2000 ICC/IF 1:50~1:100
注意事项
Cdc23/APC8 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
功能
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
