产品名称
HDAC9 (10I3) Rabbit Monoclonal Antibody
别名
HD9; Histone deacetylase 7B; HD7; HD7b; Histone deacetylase-related protein; HDAC9; HDAC7; HDAC7B; HDRP; MITR;
纯度
Affinity-chromatography
蛋白名称
HDAC7, HDAC7B, HDRP, KIAA0744, MITR
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q9UKV0
免疫原
A synthetic peptide of human HDAC9
稀释度
WB: 1:2000-1:10000 IHC: 1:50 ICC/IF: 1:50 FC: 1:50 IP: 1:20
注意事项
HDAC9 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Broadly expressed, with highest levels in brain, heart, muscle and testis. Isoform 3 is present in human bladder carcinoma cells (at protein level).
功能
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription.