产品名称
STAT5b (5J16) Rabbit Monoclonal Antibody
别名
Signal transducer and activator of transcription 5B; STA5B; STAT5; Stat5b; Transcription factor STAT5B;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P51692
免疫原
Recombinant protein of human STAT5b
稀释度
WB: 1:2000 IHC: 1:200 ICC/IF: 1:100 FC: 1:40 IP: 1:40
注意事项
STAT5b Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cytoplasm {ECO:0000250|UniProtKB:P42232}. Nucleus {ECO:0000250|UniProtKB:P42232}. Note=Translocated into the nucleus in response to phosphorylation.
功能
Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription. Positively regulates hematopoietic/erythroid differentiation.
