产品名称
MARCO Rabbit Polyclonal Antibody
蛋白名称
Macrophage receptor MARCO (Macrophage receptor with collagenous structure) (Scavenger receptor class A member 2)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9UEW3
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UEW3/entry
Mouse Swissprot No.
Q60754
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q60754
免疫原
Synthesized peptide derived from human protein . at AA range: 380-460
特异性
MARCO Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008],
组织表达
Expressed in alveolar macrophages (at protein level). Detected in macrophages from various tissues including thymus, kidney, Kupffer cells of liver, and spleen (PubMed:9468508).
细胞定位
Cell membrane ; Single-pass type II membrane protein .
功能
function:Binds Gram-positive and Gram-negative bacteria.,similarity:Contains 1 collagen-like domain.,similarity:Contains 1 SRCR domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
