产品名称
IRF6 (16O9) Rabbit Monoclonal Antibody
别名
Interferon regulatory factor 6; IRF 6; LPS;OFC 6; PIT; PPS; PPS1; VWS; VWS1;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
O14896
稀释度
WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
注意事项
IRF6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in normal mammary epithelial cells. Expression is reduced or absent in breast carcinomas
细胞定位
Nucleus. Cytoplasm Note=Translocates to nucleus in response to an activating signal
功能
Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development (By similarity). Plays a role in regulating mammary epithelial cell proliferation (By similarity). May regulate WDR65 transcription (By similarity).
