产品名称
LRP4 Rabbit Polyclonal Antibody
基因名称
LRP4 KIAA0816 LRP10 MEGF7
蛋白名称
Low-density lipoprotein receptor-related protein 4 (LRP-4) (Multiple epidermal growth factor-like domains 7)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
O75096
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O75096/entry
Mouse Swissprot No.
Q8VI56
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8VI56
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q9QYP1
免疫原
Synthesized peptide derived from human protein . at AA range: 290-370
特异性
LRP4 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the low-density lipoprotein receptor-related protein family. The encoded protein may be a regulator of Wnt signaling. Mutations in this gene are associated with Cenani-Lenz syndrome. [provided by RefSeq, May 2010],
组织表达
Expressed in bone; present in osteoblasts and osteocytes. No expression is observed in osteoclast. Expressed in several regions of the brain.
细胞定位
Cell membrane ; Single-pass type I membrane protein .
功能
function:Potential cell surface endocytic receptor, which binds and internalizes extracellular ligands for degradation by lysosomes.,similarity:Belongs to the LDLR family.,similarity:Contains 20 LDL-receptor class B repeats.,similarity:Contains 3 EGF-like domains.,similarity:Contains 8 LDL-receptor class A domains.,tissue specificity:Expressed in several regions of the brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
