产品名称
OPRD1 (18U12) Rabbit Monoclonal Antibody
别名
Delta type opioid receptor; Delta type opioid receptor DOR1; DOR 1; mDOR; Nbor; Opioid receptor delta 1; OPRD 1;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P41143
稀释度
WB 1:1000~1:2000 FC 1:50
注意事项
OPRD1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Detected in oocytes (at protein level). Detected in brain cortex, hypothalamus, hippocampus and olfactory bulb. Detected in oocytes.
细胞定位
Cell membrane; Multi-pass membrane protein
功能
G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
