产品名称
IL1RA (3V4) Rabbit Monoclonal Antibody
别名
DIRA; ICIL1RA; IL-1ra; IL-1ra3; IL-1RN; IL1 inhibitor; IL1F3; IL1RN (IL1F3); Interleukin-1 receptor antagonist protein; IRAP; Type II interleukin 1 receptor antagonist;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P18510
免疫原
A synthetic peptide of human IL1RA
稀释度
WB: 1:5000 IHC: 1:50 ICC/IF: 1:100 FC: 1:20 IP: 1:20
注意事项
IL1RA Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
The intracellular form of IL1RN is predominantly expressed in epithelial cells
细胞定位
[Isoform 1]: Secreted. [Isoform 3]: Cytoplasm.
功能
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.
